Pyridine, 2-(2-amino-5-bromobenzoyl)

Pyridine, 2-(2-amino-5-bromobenzoyl) - Names and Identifiers

Name	2-amino-5-bromobenzoylpyridine
Synonyms	Bromazepam EP Impurity A 2-amino-5-bromobenzoylpyridine 2-(2-Amino-5-bromobenzoyl)pyridine 2-(2-Amino-5-Bromobenzoyl) Pyridine 2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE Pyridine, 2-(2-amino-5-bromobenzoyl) 4-bromo-2-[(pyridin-2-yl)carbonyl]aniline (2-Amino-5-bromophenyl)(2-pyridinyl)methanone (2-amino-5-bromophenyl)-pyridin-2-ylmethanone (2-amino-5-bromophenyl)(pyridin-2-yl)methanone Methanone, (2-amino-5-bromophenyl)-2-pyridinyl- (2-azanyl-5-bromo-phenyl)-pyridin-2-yl-methanone
CAS	1563-56-0
EINECS	216-352-5
InChI	InChI=1/C12H9BrN2O/c13-8-4-5-10(14)9(7-8)12(16)11-3-1-2-6-15-11/h1-7H,14H2

Pyridine, 2-(2-amino-5-bromobenzoyl) - Physico-chemical Properties

Molecular Formula	C12H9BrN2O
Molar Mass	277.12
Density	1.546
Melting Point	98-100℃
Boling Point	451℃
Flash Point	227℃
Solubility	DMSO (Slightly), Methanol (Sparingly)
Vapor Presure	2.48E-08mmHg at 25°C
Appearance	Yellow solid
Color	Light Yellow to Yellow
pKa	2.66±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.658

Pyridine, 2-(2-amino-5-bromobenzoyl) - Introduction

It is an organic compound with the chemical formula C12H9BrN2O. The following is a description of its nature, use, preparation and safety information:

Nature:
is a solid with white to yellowish crystals. It is relatively stable at room temperature, but may decompose at high temperatures. Its melting point is about 142-146 degrees Celsius.

Use:
As an important intermediate compound, it is widely used in organic synthesis reactions. It is commonly used in the synthesis of antibacterials of the class of deaminated streptomycins, and its derivatives are used as drugs to inhibit the growth of bacteria.

Method:
Synthesis can be carried out through the following steps:
1. React 2-amino-5-bromobenzoic acid with pyridine under alkaline conditions to generate the intermediate of pyridine.
2. Heat-treat the intermediate under acidic conditions to obtain the target product.

Safety Information:
is a chemical that should be used with caution. It can cause irritation and damage to the eyes, skin and respiratory system. Wear appropriate personal protective equipment such as glasses, gloves and respiratory protection when operating. At the same time, ensure that the operation is carried out under well-ventilated conditions and avoid inhaling its dust or touching the skin. In case of accidental contact or ingestion, seek medical attention immediately.

Last Update：2024-04-09 21:11:58